Uncharted Waters: Super-Concentrated Electrolytes

Scenarios: Uncharted Waters Ahead

Guidance in sepsis management: navigating uncharted waters?

Guidelines can influence physicians to act against their better judgement. For example, while only 47% of surveyed intensivists believed that central venous pressure should guide resuscitation, 86% used it because of the SSC recommendation [2]. Protocols may improve care, but what should one do when audited patient outcomes are already better than those achieved by guideline interventions – suc...

Perfecting nerve-sparing radical prostatectomy: sailing in uncharted waters.

I’m not certain where I fi rst heard this expression, but I have lived with the philosophy that if you have been given the privilege to sail in uncharted waters, you have the responsibility to make those charts. I am grateful to Dr. Gabriel Haas, Editor-in-Chief of The Canadian Journal of Urology, for his invitation to discuss my philosophy of discovery. Previously I provided a detailed descrip...

Uncharted Waters: Strategic Environmental Assessment in the UK Offshore Area

Despite its clear significance for the myriad economic, developmental and infrastructure policies of the Member States, the Strategic Environmental Assessment Directive remains one of the more mysterious and underappreciated elements of EU environmental law. This has proved to be especially true in the context of the offshore environment. Indeed, while the maritime implications of pertinent nat...

Sailing in Uncharted Waters: Carefully Navigating the Polio Endgame

In a Perspective linked to the research article by Isobel Blake and colleagues, Elizabeth Miller and T. Jacob John discuss the path towards global polio eradication and the challenges, strategies, and necessary precautions around oral polio vaccine cessation.